From Anogia, the route sidesteps the public road from the west and goes towards the region of Zominthos, after passing the church of Agios Iakinthos.

Then, it follows the asphalt road to Agia Marina spring and the church of Agios Mamas and arrives at the crossroads to the observatory of Skinakas. It continues following the central road, leaving it in the entrance of Nida plateau and crossing it on the southeast side. The wider region of Nida is considered to be a speleological heaven. The landscape around this route is generally bare and rough. At Zominthos, the unique remaining grove of maples (Acer sempervirens) in Crete and the whitethorns (Crataegus monogyna) are really impressive. Chortsisrea, a very rare Cretan endemic plant and one of the 4 endemic species in Greece, grows at the nearby plateaus and faces the danger of extinction.